Crystal structure of a junction between two Z-DNA helices

The double helix of DNA, when composed of dinucleotide purine-pyrimidine repeats, can adopt a left-handed helical structure called Z-DNA. For reasons not entirely understood, such dinucleotide repeats in genomic sequences have been associated with genomic instability leading to cancer. Adoption of t...

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Hlavní autoři: de Rosa, Matteo, de Sanctis, Daniele, Rosario, Ana Lucia, Archer, Margarida, Rich, Alexander, Athanasiadis, Alekos, Carrondo, Maria Armenia
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2010
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2889044/
https://ncbi.nlm.nih.gov/pubmed/20439751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1003182107
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