Fractalkine and CX(3)CR1 regulate hippocampal neurogenesis in adult and aged rats

Microglia have neuroprotective capacities, yet chronic activation can promote neurotoxic inflammation. Neuronal fractalkine (FKN), acting on CX(3)CR1, has been shown to suppress excessive microglia activation. We found that disruption in FKN/ CX(3)CR1 signaling in young adult rodents decreased survi...

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Bibliografiset tiedot
Päätekijät: Bachstetter, Adam D., Morganti, Josh M., Jernberg, Jennifer, Schlunk, Andrea, Mitchell, Staten H., Brewster, Kaelin W., Hudson, Charles E., Cole, Michael J, Harrison, Jeffrey K., Bickford, Paula C., Gemma, Carmelina
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2009
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2889032/
https://ncbi.nlm.nih.gov/pubmed/20018408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2009.11.022
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