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Synthesis, Biological Evaluation and Structure-Activity Relationships of Dithiolethiones as Inducers of Cytoprotective Phase 2 Enzymes

Dithiolethiones are a family of promising cancer chemopreventive agents, and induction of Phase 2 enzymes is key to their chemopreventive activities. Two dithiolethiones have been evaluated in humans for cancer prevention. While some chemopreventive activities were detected in several human studies,...

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Autors principals: Munday, Rex, Zhang, Yuesheng, Paonessa, Joseph D., Munday, Christine M., Wilkins, Alistair L., Babu, Jacob
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2888865/
https://ncbi.nlm.nih.gov/pubmed/20481594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm100425v
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