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Targeting Hedgehog - a Cancer Stem Cell Pathway
The Hedgehog (Hh) pathway has been implicated in a wide variety of human tumors, and early clinical trials with pathway antagonists have validated Hh signaling as a bona fide anti-cancer target. Despite these encouraging results, several issues surrounding the basic biology of the Hh pathway in huma...
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| 主要な著者: | , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2010
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2888641/ https://ncbi.nlm.nih.gov/pubmed/20530699 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-09-2846 |
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