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Caspase Recruitment Domain-containing Protein 8 (CARD8) Negatively Regulates NOD2-mediated Signaling

Caspase activating and recruitment domain 8 (CARD8) has been implicated as a co-regulator of several pro-inflammatory and apoptotic signaling pathways. In the present study, we demonstrate a specific modulation of NOD2-induced signaling by CARD8 in intestinal epithelial cells. We show that CARD8 phy...

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Detalhes bibliográficos
Main Authors: von Kampen, Oliver, Lipinski, Simone, Till, Andreas, Martin, Seamus J., Nietfeld, Wilfried, Lehrach, Hans, Schreiber, Stefan, Rosenstiel, Philip
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2888403/
https://ncbi.nlm.nih.gov/pubmed/20385562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.127480
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