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B cells from rheumatoid arthritis patients show important alterations in the expression of CD86 and FcγRIIb, which are modulated by anti-tumor necrosis factor therapy

INTRODUCTION: Several molecules help preserve peripheral B cell tolerance, but when altered, they may predispose to autoimmunity. This work studied the expression of the costimulatory molecule CD86 and the inhibitory receptor for IgG immune complexes FcγRIIb (CD32b), on B cells from rheumatoid arthr...

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Main Authors: Catalán, Diego, Aravena, Octavio, Sabugo, Francisca, Wurmann, Pamela, Soto, Lilian, Kalergis, Alexis M, Cuchacovich, Miguel, Aguillón, Juan C
Formáid: Artigo
Teanga:Inglês
Foilsithe: BioMed Central 2010
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2888223/
https://ncbi.nlm.nih.gov/pubmed/20398308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar2985
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