B cells from rheumatoid arthritis patients show important alterations in the expression of CD86 and FcγRIIb, which are modulated by anti-tumor necrosis factor therapy

INTRODUCTION: Several molecules help preserve peripheral B cell tolerance, but when altered, they may predispose to autoimmunity. This work studied the expression of the costimulatory molecule CD86 and the inhibitory receptor for IgG immune complexes FcγRIIb (CD32b), on B cells from rheumatoid arthr...

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Detalhes bibliográficos
Main Authors: Catalán, Diego, Aravena, Octavio, Sabugo, Francisca, Wurmann, Pamela, Soto, Lilian, Kalergis, Alexis M, Cuchacovich, Miguel, Aguillón, Juan C
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Research article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2888223/
https://ncbi.nlm.nih.gov/pubmed/20398308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar2985
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