Attenuation of fibrosis in vitro and in vivo with SPARC siRNA

INTRODUCTION: SPARC is a matricellular protein, which, along with other extracellular matrix components including collagens, is commonly over-expressed in fibrotic diseases. The purpose of this study was to examine whether inhibition of SPARC can regulate collagen expression in vitro and in vivo, an...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Wang, Jiu-Cun, Lai, Syeling, Guo, Xinjian, Zhang, Xuefeng, de Crombrugghe, Benoit, Sonnylal, Sonali, Arnett, Frank C, Zhou, Xiaodong
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2010
Sujets:
Research article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2888211/
https://ncbi.nlm.nih.gov/pubmed/20359365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar2973
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