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siRNAs targeted to Smad4 prevent renal fibrosis in vivo
Renal fibrosis is the final common pathway leading to decreased renal function. No therapy has been established to prevent it. In order to establish a therapeutic approach and target molecule for renal fibrosis, we investigated the effects of Smad4 knockdown by siRNAs on renal fibrosis in vivo. Rena...
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| Main Authors: | , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Nature Publishing Group
2014
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4168270/ https://ncbi.nlm.nih.gov/pubmed/25236771 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep06424 |
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