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Identification of a protein–protein interaction between KCNE1 and the activation gate machinery of KCNQ1

KCNQ1 channels assemble with KCNE1 transmembrane (TM) peptides to form voltage-gated K(+) channel complexes with slow activation gate opening. The cytoplasmic C-terminal domain that abuts the KCNE1 TM segment has been implicated in regulating KCNQ1 gating, yet its interaction with KCNQ1 has not been...

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Detalhes bibliográficos
Main Authors: Lvov, Anatoli, Gage, Steven D., Berrios, Virla M., Kobertz, William R.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2888057/
https://ncbi.nlm.nih.gov/pubmed/20479109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.200910386
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