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Retinoid-induced Histone Deacetylation Inhibits Telomerase Activity in Estrogen Receptor-negative Breast Cancer Cells

BACKGROUND: Multiple mechanisms regulate cancer-associated telomerase activity at the level of human telomerase reverse transcriptase (hTERT) transcription which may serve as novel targets for anticancer approaches. MATERIALS AND METHODS: The effects of prolonged all-trans retinoic acid (ATRA) expos...

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Detalhes bibliográficos
Main Authors: Phipps, Sharla M.O., Love, William K., White, Teresa, Andrews, Lucy G., Tollefsbol, Trygve O.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2888005/
https://ncbi.nlm.nih.gov/pubmed/20044602
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