NADase as a target molecule of in vivo suppression of the toxicity in the invasive M-1 group A Streptococcal isolates

BACKGROUND: NAD-glycohydrolase (NADase) secreted by M-1 group A streptococcal (GAS) isolates are suspected as one of the virulence factors to cause severe invasive disease including streptococcal toxic shock-like syndrome (STSS). M-1 GAS strains were divided into three groups based on NADase activit...

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Main Authors: Tatsuno, Ichiro, Isaka, Masanori, Minami, Masaaki, Hasegawa, Tadao
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2010
Teme:
Research article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2887803/
https://ncbi.nlm.nih.gov/pubmed/20470439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2180-10-144
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