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Role of NADase in Virulence in Experimental Invasive Group A Streptococcal Infection

Group A streptococci (GAS) produce several exoproteins that are thought to contribute to the pathogenesis of human infection. Two such proteins, streptolysin O (SLO) and NAD(+)-glycohydrolase (NADase), have been shown to interact functionally as a compound signaling toxin. When GAS are bound to the...

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Autori principali: Bricker, Angela L., Carey, Vincent J., Wessels, Michael R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2005
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1230891/
https://ncbi.nlm.nih.gov/pubmed/16177331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.73.10.6562-6566.2005
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