Overexpression of CDC25B, CDC25C and phospho-CDC25C (Ser216) in vulvar squamous cell carcinomas are associated with malignant features and aggressive cancer phenotypes

BACKGROUND: CDC25 phosphatases are important regulators of the cell cycle. Their abnormal expression detected in a number of tumors implies that their dysregulation is involved in malignant transformation. However, the role of CDC25s in vulvar cancer is still unknown. To shed light on their roles in...

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Autori principali: Wang, Zhihui, Trope, Claes G, Flørenes, Vivi Ann, Suo, Zhenhe, Nesland, Jahn M, Holm, Ruth
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2010
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2887779/
https://ncbi.nlm.nih.gov/pubmed/20500813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-10-233
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