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The clinicopathological and prognostic impact of 14-3-3 sigma expression on vulvar squamous cell carcinomas
BACKGROUND: 14-3-3 sigma (σ) promotes G2/M cell cycle arrest by sequestering cyclin B1-CDC2 complex in cytoplasm. Down-regulation of 14-3-3σ, which has been demonstrated in various carcinomas, may contribute to malignant transformation. However, the exact role of 14-3-3σ in the pathogenesis of vulva...
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| Hoofdauteurs: | , , , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
BioMed Central
2008
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2577690/ https://ncbi.nlm.nih.gov/pubmed/18950492 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-8-308 |
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