The clinicopathological and prognostic impact of 14-3-3 sigma expression on vulvar squamous cell carcinomas

BACKGROUND: 14-3-3 sigma (σ) promotes G2/M cell cycle arrest by sequestering cyclin B1-CDC2 complex in cytoplasm. Down-regulation of 14-3-3σ, which has been demonstrated in various carcinomas, may contribute to malignant transformation. However, the exact role of 14-3-3σ in the pathogenesis of vulva...

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Autori principali: Wang, Zhihui, Tropè, Claes G, Suo, Zhenhe, Trøen, Gunhild, Yang, Guanrui, Nesland, Jahn M, Holm, Ruth
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2008
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2577690/
https://ncbi.nlm.nih.gov/pubmed/18950492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-8-308
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