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N-Triflylthiophosphoramide Catalyzed Enantioselective Mukaiyama Aldol Reaction of Aldehydes with Silyl Enol Ethers of Ketones

[Image: see text] The first Brønsted acid catalyzed asymmetric Mukaiyama aldol reaction of aldehydes using silyl enol ethers of ketones as nucleophiles has been reported. A variety of aldehydes and silyl enol ethers of ketones afforded the aldol products in excellent yields and good to excellent ena...

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Detalhes bibliográficos
Main Authors: Cheon, Cheol Hong, Yamamoto, Hisashi
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2887700/
https://ncbi.nlm.nih.gov/pubmed/20465277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol100233t
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