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Androgens Induce Functional CXCR4 through ERG Factor Expression in TMPRSS2-ERG Fusion-Positive Prostate Cancer Cells

TMPRSS2-ERG fusion transcripts have been shown to be expressed in a majority of prostate cancer (PC) patients because of chromosomal translocations or deletions involving the TMPRSS2 gene promoter and the ERG gene coding sequence. These alterations cause androgen-dependent ERG transcription factor e...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Cai, Juan, Kandagatla, Pridvi, Singareddy, Rajareddy, Kropinski, Anthony, Sheng, Shijie, Cher, Michael L., Chinni, Sreenivasa R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Neoplasia Press Inc. 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2887649/
https://ncbi.nlm.nih.gov/pubmed/20563261
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