Tetherin Restricts Productive HIV-1 Cell-to-Cell Transmission

The IFN-inducible antiviral protein tetherin (or BST-2/CD317/HM1.24) impairs release of mature HIV-1 particles from infected cells. HIV-1 Vpu antagonizes the effect of tetherin. The fate of virions trapped at the cell surface remains poorly understood. Here, we asked whether tetherin impairs HIV cel...

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Main Authors: Casartelli, Nicoletta, Sourisseau, Marion, Feldmann, Jerome, Guivel-Benhassine, Florence, Mallet, Adeline, Marcelin, Anne-Geneviève, Guatelli, John, Schwartz, Olivier
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2010
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2887479/
https://ncbi.nlm.nih.gov/pubmed/20585562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000955
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