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HIV-1 Nef promotes the localization of Gag to the cell membrane and facilitates viral cell-to-cell transfer

BACKGROUND: Newly synthesized HIV-1 particles assemble at the plasma membrane of infected cells, before being released as free virions or being transferred through direct cell-to-cell contacts to neighboring cells. Localization of HIV-1 Gag precursor at the cell membrane is necessary and sufficient...

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Autors principals: Malbec, Marine, Sourisseau, Marion, Guivel-Benhassine, Florence, Porrot, Françoise, Blanchet, Fabien, Schwartz, Olivier, Casartelli, Nicoletta
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3734038/
https://ncbi.nlm.nih.gov/pubmed/23899341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-10-80
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