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The antiviral factor APOBEC3G improves CTL recognition of cultured HIV-infected T cells
The cytidine deaminase APOBEC3G (A3G) enzyme exerts an intrinsic anti–human immunodeficiency virus (HIV) defense by introducing lethal G-to-A hypermutations in the viral genome. The HIV-1 viral infectivity factor (Vif) protein triggers degradation of A3G and counteracts this antiviral effect. The im...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2812543/ https://ncbi.nlm.nih.gov/pubmed/20038599 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20091933 |
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