CTL Escape Mediated by Proteasomal Destruction of an HIV-1 Cryptic Epitope

Cytotoxic CD8+ T cells (CTLs) play a critical role in controlling viral infections. HIV-infected individuals develop CTL responses against epitopes derived from viral proteins, but also against cryptic epitopes encoded by viral alternative reading frames (ARF). We studied here the mechanisms of HIV-...

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Detalhes bibliográficos
Main Authors: Cardinaud, Sylvain, Consiglieri, Gesa, Bouziat, Romain, Urrutia, Alejandra, Graff-Dubois, Stéphanie, Fourati, Slim, Malet, Isabelle, Guergnon, Julien, Guihot, Amélie, Katlama, Christine, Autran, Brigitte, van Endert, Peter, Lemonnier, François A., Appay, Victor, Schwartz, Olivier, Kloetzel, Peter M., Moris, Arnaud
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3093368/
https://ncbi.nlm.nih.gov/pubmed/21589903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1002049
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