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BMP-2/6 Heterodimer Is More Effective than BMP-2 or BMP-6 Homodimers as Inductor of Differentiation of Human Embryonic Stem Cells

BACKGROUND: Bone Morphogenetic Protein (BMP) signaling pathways are involved in differentiation of stem cells into diverse cell types, and thus BMPs can be used as main guidance molecules for in vitro differentiation of human stem cells. METHODOLOGY/PRINCIPAL FINDINGS: We have analyzed the ability f...

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Autori principali: Valera, Elvira, Isaacs, Michael J., Kawakami, Yasuhiko, Izpisúa Belmonte, Juan Carlos, Choe, Senyon
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2887366/
https://ncbi.nlm.nih.gov/pubmed/20567515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0011167
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