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BMP-2/6 Heterodimer Is More Effective than BMP-2 or BMP-6 Homodimers as Inductor of Differentiation of Human Embryonic Stem Cells

BACKGROUND: Bone Morphogenetic Protein (BMP) signaling pathways are involved in differentiation of stem cells into diverse cell types, and thus BMPs can be used as main guidance molecules for in vitro differentiation of human stem cells. METHODOLOGY/PRINCIPAL FINDINGS: We have analyzed the ability f...

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Détails bibliographiques
Auteurs principaux: Valera, Elvira, Isaacs, Michael J., Kawakami, Yasuhiko, Izpisúa Belmonte, Juan Carlos, Choe, Senyon
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2887366/
https://ncbi.nlm.nih.gov/pubmed/20567515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0011167
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