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Bone Morphogenetic Protein-2 and -6 Heterodimer Illustrates the Nature of Ligand-Receptor Assembly
TGF-β superfamily ligands are homo- or heterodimeric and recruit two type I and two type II Ser/Thr kinase receptors to initiate a transmembrane signaling cascade. Even with the known structure of the homodimer ligands in complex with extracellular domains of both receptor types, the sequential asse...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Endocrine Society
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2903903/ https://ncbi.nlm.nih.gov/pubmed/20484413 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2009-0496 |
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