Nanog binds to Smad1 and blocks bone morphogenetic protein-induced differentiation of embryonic stem cells

ES cells represent a valuable model for investigating early embryo development and hold promise for future regenerative medicine strategies. The self-renewal of pluripotent mouse ES cells has been shown to require extrinsic stimulation by the bone morphogenetic protein (BMP) and leukemia inhibitory...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Suzuki, Atsushi, Raya, Ángel, Kawakami, Yasuhiko, Morita, Masanobu, Matsui, Takaaki, Nakashima, Kinichi, Gage, Fred H., Rodríguez-Esteban, Concepción, Izpisúa Belmonte, Juan Carlos
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2006
Pynciau:
Biological Sciences
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC1502451/
https://ncbi.nlm.nih.gov/pubmed/16801560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0506945103
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