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Progesterone withdrawal increases the α4 subunit of the GABA(A) receptor in male rats in association with anxiety and altered pharmacology — a comparison with female rats

Withdrawal from the neurosteroid 3α,5α-allopregnanolone after chronic administration of progesterone increases anxiety in female rats and up-regulates the α4 subunit of the GABA(A) receptor (GABA(A)-R) in the hippocampus. We investigated if these phenomena would also occur in male rats. Progesterone...

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Autori principali: Gulinello, M., Gong, Q. H., Smith, S. S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2002
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2887344/
https://ncbi.nlm.nih.gov/pubmed/12367616
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