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Role of alkaline ceramidases in the generation of sphingosine and its phosphate in erythrocytes

Plasma sphingosine-1-phosphate (S1P) has been suggested to mainly originate from erythrocytes; however, within the erythrocyte, how sphingosine (SPH) generation—the precursor to S1P—is controlled is unknown. SPH is only generated from the hydrolysis of ceramides via ceramidases. Five human ceramidas...

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Bibliographische Detailangaben
Hauptverfasser: Xu, Ruijuan, Sun, Wei, Jin, Junfei, Obeid, Lina M., Mao, Cungui
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Federation of American Societies for Experimental Biology 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2887272/
https://ncbi.nlm.nih.gov/pubmed/20207939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.09-153635
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