Substrate Specificity, Membrane Topology, and Activity Regulation of Human Alkaline Ceramidase 2 (ACER2)

Human alkaline ceramidase 2 (ACER2) plays an important role in cellular responses by regulating the hydrolysis of ceramides in cells. Here we report its biochemical characterization, membrane topology, and activity regulation. Recombinant ACER2 was expressed in yeast mutant cells (Δypc1Δydc1) that l...

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Detaylı Bibliyografya
Asıl Yazarlar: Sun, Wei, Jin, Junfei, Xu, Ruijuan, Hu, Wei, Szulc, Zdzislaw M., Bielawski, Jacek, Obeid, Lina M., Mao, Cungui
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Biochemistry and Molecular Biology 2010
Konular:
Lipids
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2838321/
https://ncbi.nlm.nih.gov/pubmed/20089856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.069203
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