Cockayne syndrome group B protein promotes mitochondrial DNA stability by supporting the DNA repair association with the mitochondrial membrane

Cockayne syndrome (CS) is a human premature aging disorder associated with severe developmental deficiencies and neurodegeneration, and phenotypically it resembles some mitochondrial DNA (mtDNA) diseases. Most patients belong to complementation group B, and the CS group B (CSB) protein plays a role...

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Main Authors: Aamann, Maria D., Sorensen, Martin M., Hvitby, Christina, Berquist, Brian R., Muftuoglu, Meltem, Tian, Jingyan, de Souza-Pinto, Nadja C., Scheibye-Knudsen, Morten, Wilson, David M., Stevnsner, Tinna, Bohr, Vilhelm A.
פורמט: Artigo
שפה:Inglês
יצא לאור: The Federation of American Societies for Experimental Biology 2010
נושאים:
Research Communications
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2887265/
https://ncbi.nlm.nih.gov/pubmed/20181933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.09-147991
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