Cockayne syndrome group B protein promotes mitochondrial DNA stability by supporting the DNA repair association with the mitochondrial membrane

Cockayne syndrome (CS) is a human premature aging disorder associated with severe developmental deficiencies and neurodegeneration, and phenotypically it resembles some mitochondrial DNA (mtDNA) diseases. Most patients belong to complementation group B, and the CS group B (CSB) protein plays a role...

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Autors principals: Aamann, Maria D., Sorensen, Martin M., Hvitby, Christina, Berquist, Brian R., Muftuoglu, Meltem, Tian, Jingyan, de Souza-Pinto, Nadja C., Scheibye-Knudsen, Morten, Wilson, David M., Stevnsner, Tinna, Bohr, Vilhelm A.
Format: Artigo
Idioma:Inglês
Publicat: The Federation of American Societies for Experimental Biology 2010
Matèries:
Research Communications
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2887265/
https://ncbi.nlm.nih.gov/pubmed/20181933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.09-147991
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