Elevated CO(2) selectively inhibits interleukin-6 and tumor necrosis factor expression and decreases phagocytosis in the macrophage

Elevated blood and tissue CO(2), or hypercapnia, is common in severe lung disease. Patients with hypercapnia often develop lung infections and have an increased risk of death following pneumonia. To explore whether hypercapnia interferes with host defense, we studied the effects of elevated P(CO2) o...

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Bibliografski detalji
Glavni autori: Wang, Naizhen, Gates, Khalilah L., Trejo, Humberto, Favoreto, Silvio, Schleimer, Robert P., Sznajder, Jacob I., Beitel, Greg J., Sporn, Peter H. S.
Format: Artigo
Jezik:Inglês
Izdano: The Federation of American Societies for Experimental Biology 2010
Teme:
Research Communications
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2887258/
https://ncbi.nlm.nih.gov/pubmed/20181940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.09-136895
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