Elevated CO(2) selectively inhibits interleukin-6 and tumor necrosis factor expression and decreases phagocytosis in the macrophage

Elevated blood and tissue CO(2), or hypercapnia, is common in severe lung disease. Patients with hypercapnia often develop lung infections and have an increased risk of death following pneumonia. To explore whether hypercapnia interferes with host defense, we studied the effects of elevated P(CO2) o...

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Detalhes bibliográficos
Main Authors: Wang, Naizhen, Gates, Khalilah L., Trejo, Humberto, Favoreto, Silvio, Schleimer, Robert P., Sznajder, Jacob I., Beitel, Greg J., Sporn, Peter H. S.
Formato: Artigo
Idioma:Inglês
Publicado em: The Federation of American Societies for Experimental Biology 2010
Assuntos:
Research Communications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2887258/
https://ncbi.nlm.nih.gov/pubmed/20181940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.09-136895
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