Inhaled activated protein C protects mice from ventilator-induced lung injury

INTRODUCTION: Activated Protein C (APC), an endogenous anticoagulant, improves tissue microperfusion and endothelial cell survival in systemic inflammatory states such as sepsis, but intravenous administration may cause severe bleeding. We have thus addressed the role of APC delivered locally by inh...

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Detalhes bibliográficos
Main Authors: Maniatis, Nikolaos A, Letsiou, Eleftheria, Orfanos, Stylianos E, Kardara, Matina, Dimopoulou, Ioanna, Nakos, Georgios, Lekka, Marilena E, Roussos, Charalambos, Armaganidis, Apostolos, Kotanidou, Anastasia
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2887192/
https://ncbi.nlm.nih.gov/pubmed/20403177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/cc8976
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