Inhaled activated protein C protects mice from ventilator-induced lung injury

INTRODUCTION: Activated Protein C (APC), an endogenous anticoagulant, improves tissue microperfusion and endothelial cell survival in systemic inflammatory states such as sepsis, but intravenous administration may cause severe bleeding. We have thus addressed the role of APC delivered locally by inh...

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Bibliografiske detaljer
Main Authors:	Maniatis, Nikolaos A, Letsiou, Eleftheria, Orfanos, Stylianos E, Kardara, Matina, Dimopoulou, Ioanna, Nakos, Georgios, Lekka, Marilena E, Roussos, Charalambos, Armaganidis, Apostolos, Kotanidou, Anastasia
Format:	Artigo
Sprog:	Inglês
Udgivet:	BioMed Central 2010
Fag:	Research
Online adgang:	https://ncbi.nlm.nih.gov/pmc/articles/PMC2887192/ https://ncbi.nlm.nih.gov/pubmed/20403177 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/cc8976
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Inhaled activated protein C protects mice from ventilator-induced lung injury

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