Inhaled activated protein C protects mice from ventilator-induced lung injury

INTRODUCTION: Activated Protein C (APC), an endogenous anticoagulant, improves tissue microperfusion and endothelial cell survival in systemic inflammatory states such as sepsis, but intravenous administration may cause severe bleeding. We have thus addressed the role of APC delivered locally by inh...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Maniatis, Nikolaos A, Letsiou, Eleftheria, Orfanos, Stylianos E, Kardara, Matina, Dimopoulou, Ioanna, Nakos, Georgios, Lekka, Marilena E, Roussos, Charalambos, Armaganidis, Apostolos, Kotanidou, Anastasia
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2010
Pynciau:
Research
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2887192/
https://ncbi.nlm.nih.gov/pubmed/20403177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/cc8976
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