Effect of dexmedetomidine versus lorazepam on outcome in patients with sepsis: an a priori-designed analysis of the MENDS randomized controlled trial

INTRODUCTION: Benzodiazepines and α(2 )adrenoceptor agonists exert opposing effects on innate immunity and mortality in animal models of infection. We hypothesized that sedation with dexmedetomidine (an α(2 )adrenoceptor agonist), as compared with lorazepam (a benzodiazepine), would provide greater...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Pandharipande, Pratik P, Sanders, Robert D, Girard, Timothy D, McGrane, Stuart, Thompson, Jennifer L, Shintani, Ayumi K, Herr, Daniel L, Maze, Mervyn, Ely, E Wesley
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2887145/
https://ncbi.nlm.nih.gov/pubmed/20233428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/cc8916
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados