Dexmedetomidine or Propofol for Sedation in Mechanically Ventilated Adults with Sepsis

BACKGROUND: Guidelines currently recommend targeting light sedation with dexmedetomidine or propofol for adults receiving mechanical ventilation. Differences exist between these sedatives in arousability, immunity, and inflammation. Whether they affect outcomes differentially in mechanically ventila...

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Detalhes bibliográficos
Publicado no:N Engl J Med
Main Authors: Hughes, Christopher G., Mailloux, Patrick T., Devlin, John W., Swan, Joshua T., Sanders, Robert D., Anzueto, Antonio, Jackson, James C., Hoskins, Aimee S., Pun, Brenda T., Orun, Onur M., Raman, Rameela, Stollings, Joanna L., Kiehl, Amy L., Duprey, Matthew S., Bui, Lan N., O’Neal, Hollis R., Snyder, Allison, Gropper, Michael A., Guntupalli, Kalpalatha K., Stashenko, Gregg J., Patel, Mayur B., Brummel, Nathan E., Girard, Timothy D., Dittus, Robert S., Bernard, Gordon R., Ely, E. Wesley, Pandharipande, Pratik P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8162695/
https://ncbi.nlm.nih.gov/pubmed/33528922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1056/NEJMoa2024922
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