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Direct Visualization of Protease Action on Collagen Triple Helical Structure

Enzymatic processing of extracellular matrix (ECM) macromolecules by matrix metalloproteases (MMPs) is crucial in mediating physiological and pathological cell processes. However, the molecular mechanisms leading to effective physiological enzyme-ECM interactions remain elusive. Only scant informati...

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Autori principali: Rosenblum, Gabriel, Van den Steen, Philippe E., Cohen, Sidney R., Bitler, Arkady, Brand, David D., Opdenakker, Ghislain, Sagi, Irit
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2886829/
https://ncbi.nlm.nih.gov/pubmed/20585385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0011043
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