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Direct Visualization of Protease Action on Collagen Triple Helical Structure

Enzymatic processing of extracellular matrix (ECM) macromolecules by matrix metalloproteases (MMPs) is crucial in mediating physiological and pathological cell processes. However, the molecular mechanisms leading to effective physiological enzyme-ECM interactions remain elusive. Only scant informati...

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Detalhes bibliográficos
Main Authors: Rosenblum, Gabriel, Van den Steen, Philippe E., Cohen, Sidney R., Bitler, Arkady, Brand, David D., Opdenakker, Ghislain, Sagi, Irit
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2886829/
https://ncbi.nlm.nih.gov/pubmed/20585385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0011043
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