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Direct Visualization of Protease Action on Collagen Triple Helical Structure

Enzymatic processing of extracellular matrix (ECM) macromolecules by matrix metalloproteases (MMPs) is crucial in mediating physiological and pathological cell processes. However, the molecular mechanisms leading to effective physiological enzyme-ECM interactions remain elusive. Only scant informati...

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Bibliografiske detaljer
Main Authors: Rosenblum, Gabriel, Van den Steen, Philippe E., Cohen, Sidney R., Bitler, Arkady, Brand, David D., Opdenakker, Ghislain, Sagi, Irit
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2886829/
https://ncbi.nlm.nih.gov/pubmed/20585385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0011043
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