Omi/HtrA2 protease is associated with tubular cell apoptosis and fibrosis induced by unilateral ureteral obstruction

Kidney fibrosis, a typical characteristic of chronic renal disease, is associated with tubular epithelial cell apoptosis. The results of our recent studies have shown that Omi/HtrA2 (Omi), a proapoptotic mitochondrial serine protease, performs a crucial function in renal tubular epithelial apoptotic...

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Hlavní autoři: Kim, Jinu, Kim, Dong Sun, Park, Mae Ja, Cho, Hee-Jung, Zervos, Antonis S., Bonventre, Joseph V., Park, Kwon Moo
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2010
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2886814/
https://ncbi.nlm.nih.gov/pubmed/20219823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00737.2009
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