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Effects of adiponectin deficiency on structural and metabolic remodeling in mice subjected to pressure overload

Recent data suggest adiponectin, an adipocyte-derived hormone, affects development of heart failure in response to hypertension. Severe short-term pressure overload [1–3 wk of transverse aortic constriction (TAC)] in adiponectin(−/−) mice causes greater left ventricle (LV) hypertrophy than in wild-t...

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Detalhes bibliográficos
Main Authors: O'Shea, Karen M., Chess, David J., Khairallah, Ramzi J., Rastogi, Sharad, Hecker, Peter A., Sabbah, Hani N., Walsh, Kenneth, Stanley, William C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2886648/
https://ncbi.nlm.nih.gov/pubmed/20348222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00957.2009
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