The antioxidant tempol attenuates pressure overload-induced cardiac hypertrophy and contractile dysfunction in mice fed a high-fructose diet

We have previously shown that high-sugar diets increase mortality and left ventricular (LV) dysfunction during pressure overload. The mechanisms behind these diet-induced alterations are unclear but may involve increased oxidative stress in the myocardium. The present study examined whether high-fru...

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Main Authors: Chess, David J., Xu, Wenhong, Khairallah, Ramzi, O'Shea, Karen M., Kop, Willem J., Azimzadeh, Agnes M., Stanley, William C.
Formato: Artigo
Idioma:Inglês
Publicado: American Physiological Society 2008
Assuntos:
Translational Physiology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2614538/
https://ncbi.nlm.nih.gov/pubmed/18931030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00563.2008
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