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Sensitivity of NOS-dependent vascular relaxation pathway to mineralocorticoid receptor blockade in caveolin-1-deficient mice

Endothelial caveolin-1 (cav-1) is an anchoring protein in plasma membrane caveolae where it binds endothelial nitric oxide synthase (eNOS) and limits its activation, particularly in animals fed a high salt (HS) diet. Cav-1 also interacts with steroid receptors such as the mineralocorticoid receptor...

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Detalhes bibliográficos
Main Authors: Pojoga, Luminita H., Adamová, Zuzana, Kumar, Abhinav, Stennett, Amanda K., Romero, Jose R., Adler, Gail K., Williams, Gordon H., Khalil, Raouf A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2886646/
https://ncbi.nlm.nih.gov/pubmed/20363891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00661.2009
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