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From Sensors to Silencers: Quinoline- and Benzimidazole-Sulfonamides as Inhibitors for Zinc Proteases
[Image: see text] Derived from the extensive work in the area of small molecule zinc(II) ion sensors, chelating fragment libraries of quinoline- and benzimidazole-sulfonamides have been prepared and screened against several different zinc(II)-dependent matrix metalloproteinases (MMPs). The fragments...
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| Hoofdauteurs: | , , , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
American Chemical Society
2010
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| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2886603/ https://ncbi.nlm.nih.gov/pubmed/20507095 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja101088j |
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