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A model of GLP-1 action on insulin secretion in nondiabetic subjects

Glucagon-like peptide-1 (GLP-1)-based therapies for diabetes have aroused interest because of their effects on insulin secretion and glycemic control. However, a mechanistic model enabling quantitation of pancreatic response to GLP-1 has never been developed. To develop such a model we studied 88 he...

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מידע ביבליוגרפי
Main Authors: Dalla Man, Chiara, Micheletto, Francesco, Sathananthan, Airani, Rizza, Robert A., Vella, Adrian, Cobelli, Claudio
פורמט: Artigo
שפה:Inglês
יצא לאור: American Physiological Society 2010
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2886533/
https://ncbi.nlm.nih.gov/pubmed/20179243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00705.2009
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