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Model-Based Quantification of Glucagon-Like Peptide-1–Induced Potentiation of Insulin Secretion in Response to a Mixed Meal Challenge

Background: Glucagon-like peptide-1 (GLP-1) is a powerful insulin secretagogue that is secreted in response to meal ingestion. The ability to quantify the effect of GLP-1 on insulin secretion could provide insights into the pathogenesis and treatment of diabetes. We used a modification of a model of...

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Detalhes bibliográficos
Publicado no:Diabetes Technol Ther
Main Authors: Dalla Man, Chiara, Micheletto, Francesco, Sathananthan, Matheni, Vella, Adrian, Cobelli, Claudio
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4717506/
https://ncbi.nlm.nih.gov/pubmed/26756104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/dia.2015.0146
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