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Generating knockout rats by transposon mutagenesis in spermatogonial stem cells
Disrupting genes in the rat on a genome-wide scale will allow the investigation of many biological processes linked to human health. Here we used transposon-mediated mutagenesis to knock out genes in rat spermatogonial stem cells. Given the capacity of the testis to support spermatogenesis from thou...
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| Main Authors: | , , , , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2010
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2886193/ https://ncbi.nlm.nih.gov/pubmed/20473302 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.1461 |
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