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Monoacylglycerol lipase regulates a fatty acid network that promotes cancer pathogenesis

Tumor cells display progressive changes in metabolism that correlate with malignancy, including development of a lipogenic phenotype. How stored fats are liberated and remodeled to support cancer pathogenesis, however, remains unknown. Here, we show that the enzyme monoacylglycerol lipase (MAGL) is...

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Detalhes bibliográficos
Main Authors: Nomura, Daniel K., Long, Jonathan Z., Niessen, Sherry, Hoover, Heather S., Ng, Shu-Wing, Cravatt, Benjamin F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2885975/
https://ncbi.nlm.nih.gov/pubmed/20079333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2009.11.027
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