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Extreme-Longevity Mutations Orchestrate Silencing of Multiple Signaling Pathways
Long-lived mutants provide unique insights into the genetic factors that limit lifespan in wild-type animals. Most mutants and RNA-interference targets found to extend life, typically by 1.5- to 2.5-fold, were discovered in C. elegans. Several longevity-assurance pathways are conserved across widely...
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| Hlavní autoři: | , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2009
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2885961/ https://ncbi.nlm.nih.gov/pubmed/19465083 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbagen.2009.05.011 |
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