Rec-8 dimorphism affects longevity, stress resistance and X-chromosome nondisjunction in C. elegans, and replicative lifespan in S. cerevisiae

A quantitative trait locus (QTL) in the nematode C. elegans, “lsq4,” was recently implicated by mapping longevity genes. QTLs for lifespan and three stress-resistance traits coincided within a span of <300 kbp, later narrowed to <200 kbp. A single gene in this interval is now shown to modulate...

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Detalhes bibliográficos
Main Authors: Ayyadevara, Srinivas, Tazearslan, Çagdas, Alla, Ramani, Jiang, James C., Jazwinski, S. Michal, Shmookler Reis, Robert J.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2014
Assuntos:
Genetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4120681/
https://ncbi.nlm.nih.gov/pubmed/25136348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2014.00211
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